By I Barry Holland,Susan P. C. Cole,Karl Kuchler, et al.Elsevier|Elsevier Science||Academic PressAdult NonfictionScienceLanguage(s): EnglishOn sale date: 13.10.2011Street date: 07.01.2003
ABC Proteins is an in-depth, updated research of all that's identified in regards to the topic so far. It discusses and compares evolution, biology and mechanism of motion of all recognized ABC proteins, together with the 1st structural reviews in addition to medical implications. it will likely be worthwhile to someone attempting to remain abreast of the most recent findings. This booklet is certain to develop into a vintage and may usually be updated.
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Extra info for ABC Proteins. From Bacteria to Man
However, the structures differ significantly at the subunit interface when dimers are present. Consequently, the faces of the domains involved in such interactions are still unclear. , Chapter 4). That is to say, the four core domains are both necessary and sufficient to mediate transmembrane translocation of solute. , Chapter 27). For many ABC transporters auxiliary domains have been recruited to add on specific functions. In bacterial uptake systems the periplasmic binding proteins (PBPs) bind substrate outside the cell membrane and deliver it to the membrane-associated transport complex (Wilkinson and Verschueren, Chapter 10).
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Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium. Nature. 1982;298:723–727. J. Nucleotide-binding by membrane components of bacterial periplasmic binding protein-dependent transport systems. EMBO J. 1985;4:1033–1040. , et al. A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria. Nature. 1986;323:448–450. , Ferro-Luzzi Ames G. ATP-binding sites in the membrane components of histidine permease, a periplasmic transport system.
ABC Proteins. From Bacteria to Man by I Barry Holland,Susan P. C. Cole,Karl Kuchler, et al.Elsevier|Elsevier Science||Academic PressAdult NonfictionScienceLanguage(s): EnglishOn sale date: 13.10.2011Street date: 07.01.2003